Table 3 of Mookherjee, Mol Vis 2011; 17:2618-2627.
SNP ID and location in WDR36 |
Allele |
Patient subgroup |
Frequency in patients (number) |
Frequency in controls (number) |
p-value |
Bonferroni corrected p-value |
OR (95% CI) |
Relative risk (95% CI) |
---|---|---|---|---|---|---|---|---|
rs1971050 (c.330+925 C>T) | C | POAG | 0.10 (67) | 0.09 (21) | 0.495 | - | - | - |
HTG | 0.13 (30) | 0.152 | - | - | - | |||
NON-HTG | 0.09 (37) | 0.961 | - | - | - | |||
T | POAG | 0.90 (579) | 0.91 (217) | 0.495 | - | - | - | |
HTG | 0.87 (202) | 0.152 | - | - | - | |||
NON-HTG | 0.91 (377) | 0.961 | - | - | - | |||
rs1993465 (c.459+183A>G) | A | POAG | 0.35 (225) | 0.32 (76) | 0.420 | - | - | - |
HTG | 0.40 (93) | 0.066 | 0.66 | - | - | |||
NON-HTG | 0.32 (132) | 0.990 | - | - | - | |||
G | POAG | 0.65 (421) | 0.68 (162) | 0.420 | - | - | - | |
HTG | 0.60 (139) | 0.066 | 0.66 | - | - | |||
NON-HTG | 0.68 (282) | 0.990 | - | - | - | |||
rs13153937 (c.460–112A>G) | A | POAG | 0.29 (185) | 0.24 (57) | 0.166 | - | - | |
HTG | 0.23 (53) | 0.777 | - | - | ||||
NON-HTG | 0.32 (132) | 0.032 | 0.32 | 1.486 (1.035–2.133) | 1.147 (1.007–1.287) | |||
G | POAG | 0.71 (461) | 0.76 (181) | 0.166 | - | - | - | |
HTG | 0.77 (179) | 0.777 | - | - | - | |||
NON-HTG | 0.68 (282) | 0.032 | 0.32 | - | - | |||
rs10038177 (c.710+30C>T) | C | POAG | 0.30 (197) | 0.22 (52) | 0.011 | 0.11 | 1.569 (1.107–2.225) | 1.119 (1.023–1.209) |
HTG | 0.32 (88) | 0.00014* | 0.0014 | 2.186 (1.458–3.277) | 1.440 (1.190–1.712) | |||
NON-HTG | 0.26 (109) | 0.202 | - | - | - | |||
T | POAG | 0.70 (449) | 0.78 (186) | 0.011 | 0.11 | - | - | |
HTG | 0.68 (144) | 0.00014* | 0.0014 | - | - | |||
NON-HTG | 0.74 (305) | 0.202 | - | - | - | |||
rs11241095 (c 772G>A, I264V) | A | POAG | 0.62 (399) | 0.62 (148) | 0.909 | - | - | - |
HTG | 0.65 (151) | 0.513 | - | - | - | |||
NON-HTG | 0.6 0 (248) | 0.566 | - | - | - | |||
G | POAG | 0.38 (247) | 0.38 (90) | 0.909 | - | - | ||
HTG | 0.35 (81) | 0.513 | - | - | - | |||
NON-HTG | 0.40 (166) | 0.566 | - | - | - | |||
rs10043631 (c.1494+90C>T) | C | POAG | 0.28 (184) | 0.27 (64) | 0.640 | - | - | - |
HTG | 0.31 (72) | 0.322 | - | - | - | |||
NON-HTG | 0.27 (112) | 0.964 | - | - | - | |||
T | POAG | 0.72 (462) | 0.73 (174) | 0.640 | - | - | - | |
HTG | 0.69 (160) | 0.322 | - | - | - | |||
NON-HTG | 0.73 (302) | 0.964 | - | - | - | |||
rs10038058 (c.1494+143G>A) | A | POAG | 0.35 (225) | 0.33 (79) | 0.650 | - | - | - |
HTG | 0.38 (88) | 0.283 | - | - | - | |||
NON-HTG | 0.33 (137) | 0.976 | - | - | - | |||
G | POAG | 0.6 5(421) | 0.67 (159) | 0.650 | - | - | - | |
HTG | 0.62 (144) | 0.283 | - | - | - | |||
NON-HTG | 0.67 (277) | 0.976 | - | - | - | |||
rs10491424 (c.1965–905C>T) | C | POAG | 0.40 (262) | 0.41 (98) | 0.868 | - | - | - |
HTG | 0.36 (84) | 0.269 | - | - | - | |||
NON-HTG | 0.43 (178) | 0.651 | - | - | ||||
T | POAG | 0.60 (384) | 0.59 (140) | 0.868 | - | - | - | |
HTG | 0.64 (148) | 0.269 | - | - | - | |||
NON-HTG | 0.57 (236) | 0.651 | - | - | - | |||
rs17553936 (c.1965–30A>G) | A | POAG | 0.64 (414) | 0.63 (151) | 0.860 | - | - | - |
HTG | 0.66 (154) | 0.505 | - | - | - | |||
NON-HTG | 0.63 (260) | 0.937 | - | - | - | |||
G | POAG | 0.36 (232) | 0.37 (87) | 0.860 | - | - | - | |
HTG | 0.34 (78) | 0.505 | - | - | - | |||
NON-HTG | 0.37 (154) | 0.937 | - | - | - | |||
rs13186912 (c.2181A>T) (V727V) | A | POAG | 0.69 (446) | 0.68 (162) | 0.782 | - | - | - |
HTG | 0.73 (169) | 0.257 | - | - | - | |||
NON-HTG | 0.67 (277) | 0.761 | - | - | - | |||
T | POAG | 0.31 (200) | 0.32 (76) | 0.782 | - | - | - | |
HTG | 0.27 (63) | 0.257 | - | - | - | |||
NON-HTG | 0.33 (137) | 0.761 | - | - | - |