Figure 4. Family 3: two affected brothers, affected paternal aunt. A: At one and one-half year of age, the proband developed left acute pupillary block glaucoma. Complete crystalline lens dislocation into the anterior chamber of the left eye and a large corneal diameter (14 mm horizontally) can be seen. B: The proband's six-month-old brother was tentatively scheduled for primary congenital glaucoma surgery by his physician. Megalocornea is evident (14 mm horizontal diameter without breaks or scarring). The child also had bilateral spherophakia (not shown). C: The paternal aunt of the proband had been diagnosed with glaucoma at ten years of age but never had surgery. At 20 years old, bilateral symmetric megalocornea (14 mm horizontal diameter without breaks or scarring) is evident. Both crystalline lenses were posteriorly dislocated (not shown). She had high intraocular pressure, angle synechiae, and glaucomatous optic nerve damage in her right eye (not shown).