Figure 4. DNA sequence of a part of the CHM gene in the unaffected men and affected individuals. A represents normal sequence. B represents a hemizygous mutation 1488delGinsATTAC in the affected man. This mutation is predicted to truncate the 653 amino acid choroideremia (CHM) protein by 157 amino acids because of the insertion of the stop codon TAA. C represents normal sequence. D represents a C to G transversion at nucleotide 1703.