Figure 4. Genetic associations with mutant Tyrp1. In BXD RI mice with mutant Tyrp1, gene ontology enrichment analysis identified two distinct clusters of biologic processes that were correlated with mutant Tyrp1. The first branch included mesenchyme development and neural crest cell development and migration. The second branch included melanin biosynthetic processes and glycoprotein metabolic processes. GO categories reaching statistical significance are indicated with a bold outline and adjusted p values.