Appendix 1. Primers used for FBN1 amplification. Summary of the primers used for the amplification of FBN1 exons. Sequences are given in the 5′→3′direction. To access the data, click or select the words “Appendix 1.” This will initiate the download of a compressed (pdf) archive that contains the file.

Appendix 2. Clinical details of the patients II:2, III:12, and family member IV:4. Each patient in the family has bilateral ectopia lentis, myopia, arachnodactyly, and joint hypermobility. Only the proband displays abnormalities of the cardiovascular system. Individual IV:4 appears normal. Abbreviations: M: male; F: female; IOL: intraocular lens; AS/H: arm span/height ratio; +: present; –: absent. N: normal. To access the data, click or select the words “Appendix 2.” This will initiate the download of a compressed (pdf) archive that contains the file.