Table 3 of
Zhang, Mol Vis 2011; 17:2325-2332. Table 3 of
Zhang, Mol Vis 2011; 17:2325-2332.
Table 3. Polymorphisms in antioxidant genes SOD1-251A/G, CAT–21A/T, GPX–198 C/T, and risk of cataract development.
| Genotype | Patients (%) | Controls (%) | OR (95% CI) | p-value |
|---|---|---|---|---|
| SOD1–251A/G | ||||
| AA | 138 (33.3) | 173 (44.8) | 0.613 (0.461–0.817) | 0.001 |
| AG | 191 (46.0) | 160 (41.5) | 1.204 (0.910–1.593) | 0.200 |
| GG | 86 (20.7) | 53 (13.7) | 1.642 (1.129–2.389) | 0.012 |
| A allele frequency | 0.563 | 0.655 | ||
| G allele frequency | 0.437 | 0.345 | 1.479 (1.208–1.810) | 0.001 |
| CAT-21A/T | ||||
| AA | 204 (49.2) | 207 (53.6) | 0.836 (0.633–1.104) | 0.229 |
| AT | 167 (40.2) | 148 (38.3) | 1.083 (0.815–1.438) | 0.613 |
| TT | 44 (10.6) | 31 (8.1) | 1.358 (0.839–2.199) | 0.226 |
| A allele frequency | 0.693 | 0.728 | ||
| T allele frequency | 0.307 | 0.272 | 1.187 (0.956–1.474) | 0.123 |
| GPX-198 C/T | ||||
| CC | 201 (48.4) | 208 (53.9) | 0.804 (0.609–1.061) | 0.137 |
| CT | 177 (42.7) | 149 (38.6) | 1.183 (0.892–1.569) | 0.250 |
| TT | 37 (8.9) | 29 (7.5) | 1.205 (0.726–2.001) | 0.521 |
| C allele frequency | 0.698 | 0.732 | ||
| T allele frequency | 0.302 | 0.268 | 1.183 (0.952–1.471) | 0.135 |