Table 7 of Chen, Mol Vis 2011; 17:2297-2310.


Table 7. Genotypes and sex hormone levels among female subjects.

  Progesterone (ng/ml) Estradiol (pg/ml) Testosterone (ng/ml)
Study population Mean Standard Deviation Mean Standard Deviation Mean Standard Deviation
rs743572 (CYP17A1)
GG (n=98) 5.33 7.13 42.98 28.69 1.41 0.86
GA (n=128) 5.98 7.30 50.53 34.26 1.64 1.35
AA (n=48) 5.71 5.22 44.39 28.08 1.67 1.07
p-value 0.780 0.171 0.257
rs6203 (HSD3B1)
TT (n=108) 5.70 7.40 44.16 30.31 1.71 1.38
TC (n=138) 5.59 6.17 48.74 33.11 1.48 0.98
CC (n=28) 6.26 8.43 46.95 27.11 1.41 0.85
p-value 0.799 0.386 0.361
rs1047303 (HSD3B1)
AA (n=236) 5.66 6.80 47.27 30.56 1.58 1.14
AC (n=38) 5.97 7.63 43.57 36.64 1.43 1.21
p-value 0.666 0.569 0.484
rs605059 (HSD17B1)
GG (n=80) 6.34 6.65 50.64 34.79 1.83 1.44
GA (n=136) 5.54 7.27 47.43 31.87 1.44 0.94
AA (n=58) 5.18 6.42 39.82 23.97 1.48 1.10
p-value 0.425 0.114 0.027
rs523349 (SRD5A2)
GG (n=86) 5.53 7.16 48.03 30.78 1.52 1.02
GC (n=132) 5.94 7.48 47.59 34.06 1.61 1.35
CC (n=56) 5.41 4.90 42.83 25.56 1.49 0.78
p-value 0.977 0.612 0.846
rs10046 (CYP19A1)
AA (n=76) 6.13 8.02 50.83 36.93 1.50 1.00
AG (n=143) 5.37 6.25 45.34 29.38 1.60 1.16
GG (n=55) 5.97 6.95 44.79 28.19 1.56 1.32
p-value 0.843 0.552 0.546