Table 6 of Chen, Mol Vis 2011; 17:2297-2310.


Table 6. Genotypes and sex hormone levels among male subjects

  Progesterone (ng/ml) Estradiol (pg/ml) Testosterone (ng/ml)
Study population Mean Standard deviation Mean Standard deviation Mean Standard deviation
rs743572 (CYP17A1)
GG (n=76) 3.12 2.01 24.27 14.44 6.10 1.80
GA (n=156) 3.45 3.88 24.34 14.19 5.75 1.87
AA (n=57) 2.99 1.69 21.55 12.48 5.75 2.16
p-value 0.494 0.358 0.438
rs6203 (HSD3B1)
TT (n=120) 3.48 4.19 23.49 14.38 5.93 1.95
TC (n=133) 3.04 2.09 24.03 13.93 5.74 1.89
CC (n=36) 3.44 1.92 23.76 12.72 5.94 1.86
p-value 0.483 0.967 0.684
rs1047303 (HSD3B1)
AA (n=239) 3.37 3.36 23.86 14.18 5.89 1.84
AC (n=48) 2.75 1.49 23.00 12.86 5.68 2.24
CC (n=2) 3.97 3.01 32.61 6.85 4.34 0.54
p-value 0.454 0.653 0.414
rs605059 (HSD17B1)
GG (n=83) 2.77 1.50 20.50 11.08 5.67 1.72
GA (n=151) 3.42 2.88 24.80 14.21 5.92 2.09
AA (n=55) 3.60 5.00 25.88 16.24 5.91 1.64
p-value 0.214 0.035 0.600
rs523349 (SRD5A2)
GG (n=110) 2.92 1.88 21.63 11.15 5.91 1.93
GC (n=138) 3.58 4.12 25.63 15.84 5.84 1.96
CC (n=41) 3.17 1.38 23.31 13.21 4.70 1.71
p-value 0.217 0.066 0.866
rs10046 (CYP19A1)
AA (n=91) 2.86 1.42 21.35 11.51 5.88 1.88
AG (n=146) 3.52 3.83 25.50 14.50 5.85 1.90
GG (n=52) 3.29 3.07 23.15 15.64 5.77 2.00
p-value 0.249 0.064 0.960