Molecular Vision: Chen, Mol Vis 2011; 17:2297-2310. Table 4

Table 4. Summary of multifactor dimensionality reduction (MDR) analysis.

	Testing results		10-fold cross-validation
Factors in the best model	Accuracy (%)	p-value^a	Consistency	p-value^a
6	46.0	0.900	3/10	1.000
2, 6	50.6	0.424	7/10	0.429
2, 6. 7	57.5	0.019	10/10	0.070
1, 2, 4, 6	46.6	0.833	5/10	0836

Factors: 1. SNP1: rs743572 (CYP17A1); 2. SNP2: rs6203 (HSD3B1); 3. SNP3: rs1047303 (HSD3B1); 4. SNP4: rs605059 (HSD17B1); 5. SNP5: rs523349 (SRD5A2); 6. SNP6: rs10046 (CYP19A1); 7. Gender. MDR searches through all possible interaction combinations among independent variables (single factor to four-factor interaction models in this study) and reports a combination that provide the best fitness in each model. ^aEmpirical p-values were calculated by permutation analysis.