Table 3 of Chen, Mol Vis 2011; 17:2297-2310.

Table 3. Pairwise stratified analysis of synergistic genotypic association.

Variable Male Female
SNP6 SNP2 OR (95% CI) p-valuea p-valueb OR (95% CI) p-valuea p-valueb
AA TT 1.00 (Reference)   0.833 1.00 (Reference)   0.113
  TC 0.96 (0.39–2.37) 0.929   2.88 (1.05–7.88) 0.040  
  CC 1.40 (0.39–5.08) 0.609   1.44 (0.31–6.62) 0.639  
AG TT 1.00 (Reference)   0.007 1.00 (Reference)   0.015
  TC 2.38 (1.17–4.83) 0.017   0.40 (0.19–0.81) 0.011  
  CC 0.42 (0.12–1.46) 0.173   0.26 (0.08–0.88) 0.030  
GG TT 1.00 (Reference)   0.207 1.00 (Reference)   0.829
  TC 0.60 (0.18–2.00) 0.406   0.71 (0.23–2.15) 0.541  
  CC 3.00 (0.48–18.60) 0.238   -    
SNP4 SNP3 OR (95% CI) p-valuea p-valueb OR (95% CI) p-valuea p-valueb
GG AA 1.00 (Reference)   0.821 1.00 (Reference)   0.609
  AC 0.73 (0.27–1.97) 0.821   0.71 (0.19–2.67) 0.609  
  CC - -   - -  
GA AA 1.00 (Reference)
0.013 1.00 (Reference)
0.253
  AC 4.32 (1.37–13.61) 0.013   0.57 (0.21–1.50) 0.253  
  CC - -   - -  
AA AA 1.00 (Reference)   0.391 1.00 (Reference)   0.835
  AC 3.38 (0.59–19.21) 0.391   1.19 (0.24–5.84) 0.835  
  CC - -   - -  

SNP2=rs6203 (HSD3B1); SNP3=rs1047303 (HSD3B1); SNP4=rs605059 (HSD17B1); SNP6=rs10046 (CYP19A1). aSpecific p-value. bGlobal p-value.

Chen, Mol Vis 2011; 17:2297-2310. http://www.molvis.org/molvis/v17/a250

©2011 Molecular Vision http://www.molvis.org/molvis/

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