Figure 2. Fundus signs of affected siblings in family 1. Fundus photographs, autofluorescence, and posterior segment optical coherence tomography (OCT) images of family 1. A: Individual II:1 (affected sister) had a completely normal left posterior segment examination but significant retinal pigment epithelium (RPE) layer thickening on the right. B: Individual II:3 (affected brother) had disruption of the inner segment: outer segment interface. C: Individual II:4 (proband) had exudative vitelliform lesions, demonstrated in the right eye.