Figure 1. Pedigree of a four-generation family harboring congenital cataract. The proband is marked with an arrow. Squares and circles indicate males and females, respectively. Black and white symbols denote affected and unaffected individuals, respectively. A slash through the symbol means that the family member is deceased. Thirty-eight individuals (eight affected and thirty unaffected) from the family were enrolled and underwent ophthalmic examinations and genetic analysis (individuals marked by an asterisk did not participate in the study).