Table 2 of
Nieto-Miguel, Mol Vis 2011; 17:2102-2117.
Table 2. Up- and down-regulated genes in cells of the limbal epithelial stem cell niche.
Symbol | Entrez gene name | Location* | Type | Fold change |
---|---|---|---|---|
CXCL12 | Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | Extracellular space | Cytokine | +26.45 |
ISL1 | ISL LIM homeobox 1 | Nucleus | Transcription regulator | +20.90 |
COL2A1 | Collagen, type II, alpha 1 | Extracellular space | Other | +19.47 |
NCAM1 | Neural cell adhesion molecule 1 | Plasma membrane | Other | +11.82 |
ABCGG2 | ATP-binding cassette, sub-family G (WHITE), member 2 | Plasma membrane | Transporter | +10.25 |
KRT15 | Keratin 15 | Cytoplasm | Other | +10.00 |
ACAN | Aggrecan | Extracellular space | Other | +9.24 |
FOXA2 | Forkhead box A2 | Nucleus | Transcription regulator | +9.24 |
GJB1 | Gap junction protein, beta 1, 32 kDa | Plasma membrane | Transporter | +9.24 |
MSX1 | Msh homeobox 1 | Nucleus | Transcription regulator | +9.24 |
CD8B | CD8b molecule | Plasma membrane | Other | +9.17 |
DHH | Desert hedgehog homolog (Drosophila) | Extracellular space | Peptidase | −17.66 |
CDC2 | Cell division cycle 2, G1 to S and G2 to M | Nucleus | Kinase | −9.33 |
GJA1 | Gap junction protein, alpha 1, 43 kDa | Plasma membrane | Transporter | −6.89 |
CCNA2 | Cyclin A2 | Nucleus | Other | −6.71 |
PARD6A | Par-6 partitioning defective 6 homolog alpha (C. elegans) | Plasma membrane | Other | −5.13 |
KAT2A | K(lysine) acetyltransferase 2A | Cytoplasm | Enzyme | −5.07 |
DVL1 | Dishevelled, dsh homolog 1 (Drosophila) | Cytoplasm | Other | −4.61 |
JAG1 | Jagged 1 (Alagille syndrome) | Extracellular space | Growth factor | −4.54 |
S100B | S100 calcium binding protein B | Cytoplasm | Other | −4.34 |
FRAT1 | Frequently rearranged in advanced T-cell lymphomas | Cytoplasm | Other | −4.28 |