Table 2 of Nieto-Miguel, Mol Vis 2011; 17:2102-2117.


Table 2. Up- and down-regulated genes in cells of the limbal epithelial stem cell niche.

Symbol Entrez gene name Location* Type Fold change
CXCL12 Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) Extracellular space Cytokine +26.45
ISL1 ISL LIM homeobox 1 Nucleus Transcription regulator +20.90
COL2A1 Collagen, type II, alpha 1 Extracellular space Other +19.47
NCAM1 Neural cell adhesion molecule 1 Plasma membrane Other +11.82
ABCGG2 ATP-binding cassette, sub-family G (WHITE), member 2 Plasma membrane Transporter +10.25
KRT15 Keratin 15 Cytoplasm Other +10.00
ACAN Aggrecan Extracellular space Other +9.24
FOXA2 Forkhead box A2 Nucleus Transcription regulator +9.24
GJB1 Gap junction protein, beta 1, 32 kDa Plasma membrane Transporter +9.24
MSX1 Msh homeobox 1 Nucleus Transcription regulator +9.24
CD8B CD8b molecule Plasma membrane Other +9.17
DHH Desert hedgehog homolog (Drosophila) Extracellular space Peptidase −17.66
CDC2 Cell division cycle 2, G1 to S and G2 to M Nucleus Kinase −9.33
GJA1 Gap junction protein, alpha 1, 43 kDa Plasma membrane Transporter −6.89
CCNA2 Cyclin A2 Nucleus Other −6.71
PARD6A Par-6 partitioning defective 6 homolog alpha (C. elegans) Plasma membrane Other −5.13
KAT2A K(lysine) acetyltransferase 2A Cytoplasm Enzyme −5.07
DVL1 Dishevelled, dsh homolog 1 (Drosophila) Cytoplasm Other −4.61
JAG1 Jagged 1 (Alagille syndrome) Extracellular space Growth factor −4.54
S100B S100 calcium binding protein B Cytoplasm Other −4.34
FRAT1 Frequently rearranged in advanced T-cell lymphomas Cytoplasm Other −4.28