Figure 2. Scatter plots comparing the copy number estimates determined for the second and third MLPA assay on all subjects. Panel A shows the results for CFHR3, Panel B for CFHR1, and Panel C for CFHR4. The scatter plots show that the MLPA ratio criteria for homozygous deletion is 0.00 to 0.40, for heterozygous deletion is 0.41 to 0.80, for wild-type is 0.81 to 1.60, and for heterozygous duplication is >1.60. The largest cluster in each panel represents two copies, the second largest cluster one copy, and the subjects on the y-axis in panels A and B zero copies.