Figure 3. Sequence analysis of CRYBA1/A3 at exon 3. A: Sequence of affected (individual V:1). B: Sequence of unaffected individual (individual IV:5). In panel A, the mutation G→T was evident at the first base of intron 3, which was identified in all patients of the family, but was not found in the unaffected family members nor in the 100 unrelated control subjects.