Figure 3. Sodium selenite induced Akt phosphorylation in a PI3-K-dependent manner either in the normal or 1,2-DHN stimulated state. The intervention duration of LY294002, sodium selenite and 1,2-DHN was 1, 12, and 24 h, respectively. Cells were harvested for western blot, and each experiment was performed in triplicate. (*p<0.05, **p<0.01).