Figure 4. SPARC promotes HTF cell-mediated collagen gel contraction. Effects of 100 ng/ml SPARC on HTF-mediated collagen contraction at different time points from 1 to 9 days. The area of collagen lattices was quantified and plotted as relative size of initial area. Shown are the means±SEM of 2 independent experiments (*p<0.01; **p<0.001; n≥10).