Figure 1. SPARC expression is increased in human Tenon’s capsule scars. Immunohistochemistry for SPARC (green) in scarred human Tenon’s capsule (C) shows a marked accumulation of SPARC around and within vessel walls (arrows) and in areas of condensed extracellular matrix (arrow heads), whereas only weak signals are detected in extracellular matrix and vessel walls (arrows) of healthy tissue (B). A: control immunostaining of a healthy Tenon’s capsule. red: propidium iodide staining; original magnification: 20×.