Table 1 of Valentincic, Mol Vis 2011; 17:2003-2010.
Inflammatory mediators | Controls (n=10) | IU patients (n=36) | Active IU (n=15) | Quiescent IU (n=21) | CME (n=7) | No CME (n=29) | Systemic therapy (n=10) | No systemic therapy (n=26) | Systemic disease (n=9) | No systemic disease (n=27) |
---|---|---|---|---|---|---|---|---|---|---|
Mean age (yrs) | 40 | 36 | 42 | 32 | 44 | 35 | 43 | 36 | 44 | 34 |
Geometric
mean (pg/ml)
Median (pg/ml) Range (pg/ml) p value |
||||||||||
IL-1β (2.0)* | 4.0 4.8 2.0–6.8 | 2.9 2.9 2.0–11.7 | 2.8 3.2 2.0–11.7 | 2.5 2.6 2.0–5.7 | 1.8 1.1 2.0–4.4 | 2.9 3.5 2.0–11.7 | 1.9 3.2 2.2–6.7 | 2.9 4.0 2.0–11.7 | 1.5 1.1 2.0–4.5 | 3.1 3.6 2.0–11.7 |
0.053 | 0.820 | 0.110 | 0.101 | 0.127 | ||||||
IL-6 (0.5) | 3.6 3.3 2.6–8.1 | 3.3 3.3 2.4–17.4 | 4.0 3.4 2.6–17.4 | 3.6 3.3 2.4–6.8 | 4.8 4.0 3.1–17.4 | 3.5 3.2 2.4–7.5 | 4.1 4.0 2.7–7.5 | 3.6 3.2 2.4–17.4 | 4.3 4.0 3.1–6.8 | 3.6 3.2 2.4–17.4 |
0.990 | 0.657 | 0.121 | 0.063 | 0.693 | ||||||
IL-8 (0.4) | 8.6 8.7 2.3–33.3 | 8.4 8.4 3.7–14.3 | 8.3 8.5 4.6–13.4 | 8.0 7.4 3.7–14.3 | 8.5 8.4 6.1–11.5 | 8.0 8.3 3.7–14.3 | 8.7 8.9 4.6–14.3 | 7.9 7.4 3.7–13.4 | 9.0 9.1 6.8–11.5 | 7.8 8.0 3.7–14.3 |
0.783 | 1.000 | 0.930 | 0.566 | 0.180 | ||||||
IL-10 (1.5) | 2.5 2.3 1.5–9.9 | 2.1 2.1 1.5–7.0 | 2.2 2.3 1.5–7.0 | 1.9 2.1 1.5–3.6 | 2.6 2.9 1.5–7.0 | 1.9 2.1 1.5–5.4 | 2.5 2.4 1.5–7.0 | 1.9 2.0 1.5–5.4 | 1.7 1.9 1.5–2.9 | 2.1 2.2 1.5–7.0 |
0.286 | 0.202 | 0.065 | 0.256 | 0.192 | ||||||
TNF-α (2.0) | 1.6 1.3 2.0–3.2 | 3.2 3.2 2.0–6.7 | 2.8 2.8 2.0–6.7 | 3.0 3.3 2.0–4.2 | 3.0 3.1 2.5–4.2 | 2.9 3.3 2.0–6.7 | 2.5 2.9 2.0–6.7 | 3.1 3.3 2.0–6.7 | 2.7 3.1 2.0–3.3 | 3.0 3.3 2.0–6.7 |
<0.0001 | 0.072 | 0.387 | 0.034 | 0.157 | ||||||
IL-12p70 (1.5) | 1.9 2.2 1.5–2.7 | 2.2 2.2 1.5–3.8 | 1.8 2.2 1.5–3.7 | 2.1 2.2 1.5–3.8 | 1.4 2.2 1.5–3.2 | 2.1 2.2 1.5–3.8 | 1.5 1.5 1.5–3.8 | 2.1 2.2 1.5–3.7 | 1.7 1.9 1.5–3.5 | 2.0 2.2 1.5–3.8 |
0.990 | 0.401 | 0.206 | 0.135 | 0.349 |