Figure 1. Pedigrees of the family affected
by NPS. Pedigree showing five consecutive generations of affected
members. Autosomal dominant transmission of the disease is evident. The
arrow at the lower left of the symbol indicates the proband, squares
indicate males and circles indicate females, open and filled symbols
indicate unaffected and affected individuals respectively. Asterisks
indicate members of the family who underwent clinical examination and
molecular analyses.