Table 2 of Ramachandran, Mol Vis 2011; 17:1877-1890. Table 2 of Ramachandran, Mol Vis 2011; 17:1877-1890.
Table 2. IC50 for inhibition of phosphorylation at Thr853 and Thr696 of MYPT1 by the Rho kinase inhibitors.
| Target/Function | Y-27632 (nM) | Y-39983 (nM) |
|---|---|---|
| Thr853 | 658 | 15 |
| Thr696 | 2270 | 177 |
| MLC | 1065 | 14 |
| Relaxation | ++ | +++++ |