Figure 4. Effect of catalin on selenite-induced lens turbidity and cataract scores. A: Percentages of the optical density (OD) for lens turbidity of the selenite -only group influenced by the presence of catalin equivalent to 0.016–0.1 μM PRX or the catalin formulated vehicle (CataV) were compared. Turbidity was determined by spectroscopy at 405 nm. *catalin (0.032–0.1 μM PRX) versus CataV at p<0.05. B: Average cataract scores of groups treated with various doses of catalin in a selenite-induced cataract rat model. Rats (n=6~20) pretreated with catalin solutions (0, 2.5, and 5 mg/kg) or the CataV administered subcutaneously for 4 days. Each lens cataract score was classified into four degrees (0–3) from clear to mature dense. The average cataract score of each group is expressed as the mean±standard error and is plotted versus the post cataract induction day. *catalin (5 mg/kg) versus Se controls at p<0.05.