Table 3 of Orr, Mol Vis 2011; 17:1850-1861.

Table 3. PolyPhen2 HumVar results of familial missense variants in PRSS56.

Mutation Result Score Sensitivity Specificity
R176G Possibly Damaging 0.522 0.82 0.81
G237R* Probably Damaging 0.940 0.64 0.92
V302F* Benign 0.480 0.83 0.80
W309S Probably Damaging 0.989 0.48 0.96
G320R* Probably Damaging 0.991 0.45 0.97
C395R* Probably Damaging 0.923 0.66 0.91
P599A Benign 0.001 0.99 0.08

*Denotes variants observed in the present study.

Orr, Mol Vis 2011; 17:1850-1861. http://www.molvis.org/molvis/v17/a202

©2011 Molecular Vision http://www.molvis.org/molvis/

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