Table 2 of Orr, Mol Vis 2011; 17:1850-1861. Table 2 of Orr, Mol Vis 2011; 17:1850-1861.
Table 2. PolyPhen2 HumDiv results of familial missense variants in PRSS56.
| Mutation | Result | Score | Sensitivity | Specificity |
|---|---|---|---|---|
| R176G | Probably Damaging | 0.981 | 0.74 | 0.96 |
| G237R* | Probably Damaging | 0.998 | 0.27 | 0.99 |
| V302F* | Possibly Damaging | 0.917 | 0.81 | 0.94 |
| W309S | Probably Damaging | 1.000 | 0.00 | 1.00 |
| G320R* | Probably Damaging | 1.000 | 0.00 | 1.00 |
| C395R* | Probably Damaging | 0.998 | 0.27 | 0.99 |
| P599A | Benign | 0.000 | 1.00 | 0.00 |