Table 2 of Ammar, Mol Vis 2011; 17:1806-1813.

Table 2. Cleaved caspase-3 positive trabecular meshwork cells at 24 h.

PGA+BB formulations (dil. 1:100) % Apoptotic cells
Travoprost+timolol with PQ 15.3%±6.3%*
Travoprost+timolol with BAK 18.7%±4.5%*
Latanoprost+timolol with BAK 11.9%±4.6%*†‡
Original % BAK (dil. 1:100) % Apoptotic cells
0% (BSS) 4.4%±2.5%
0.001% BAK 44.5%±8.1%*
0.005% BAK 15.9%±6.5%*
0.010% BAK 12.8%±6.8%*
0.015% BAK 13.2%±6.0%*
0.020% BAK 5.8%±3.5%

TM cells were treated with test and control solutions (diluted 1:100) for 25 min, and then returned to fresh culture media. Cells were fixed and immunostained for cleaved caspase-3 at 24 h. Data are reported as the percent of cleaved caspase-3 positive cells ±SD (n=5). *p<0.05 versus BSS; †=p<0.05 versus travoprost+timolol with BAK; ‡=p<0.05 versus BAK alone.

Ammar, Mol Vis 2011; 17:1806-1813. http://www.molvis.org/molvis/v17/a197

©2011 Molecular Vision http://www.molvis.org/molvis/

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