Figure 5 of Ma, Mol Vis 2011; 17:1759-1770.


Figure 5. Transplantation of murine retinal progenior cells (mRPCs) into Rho−/− mice combined with chondroitinase ABC or a cocktail. The first row (A-D) and the third row (I-L): Transplantation with chondroitinase ABC. The second row (E-H) and the fourth row (M-P): Transplantation with a cocktail. The average number of recoverin-positive (Q) or rhodopsin-positive cells (R) was counted per microscopic field. The columns are mean values, error bars are SD *p<0.05 (n=9). The cells (arrow) are recoverin-positive in the outer nuclear layers and inner nuclear layers (D, H). The cells express rhodopsin when they are transplanted with a cocktail (N). However, no rhodopsin-positive cells are seen in J. Scale bar: 20 μm (D, H, L); 10 μm (P). Abbreviations: ganglion cell layer (GCL); inner nuclear layer (INL); outer nuclear layer (ONL); and subretinal space (SRS).