Figure 4. Three weeks post transplantation of murine retinal progenior cells (mRPCs) into Rho^−/− mice. The first row (A, B, C, D) and the third row (I, J, K, L) were mRPCs groups as control. The second row (E, F, G, H) and the fourth row (M, N, O, P) were chondroitinase ABC treated groups. Q: The average number of cells in the retinal layers was counted per microscopic field. The columns are mean values, error bars are SD *p<0.01 (n=9). The chondroitin expression in F was lower than that in B. Most cells migrated into the retinal layer when Chondroitinase ABC was used (H, P). The cells express GFAP whether in the subretinal space (L) or vitreous cavity (P). None of the cells located in the retinal layers express GFAP. Scale bar: 20 μm (D, H, L, P) Abbreviations: ganglion cell layer (GCL); inner plexiform layer (IPL); inner nuclear layer (INL); outer nuclear layer (ONL); and subretinal space (SRS).