Figure 1. Chondroitinase ABC promotes the
migration of murine retinal progenior cells (mRPCs) into B6 mice. A-C:
One
week after transplantation of mRPCs. D-F: One week after
transplantation of mRPCs combined with Chondroitinase ABC. Murine
retinal progenitor cells gather in the subretinal space. Abundant of
cells migrated into the retinal layers were seen in F.
Quantification of the difference of migration distance from the
injection site (G) and the cells in the retinal layers (H).
The
cells in the chondroitinase ABC treated group have a higher ability
to migrate and survive in the retinal layers. Scale bar: 25 μm (C, F).
G, H: The columns are mean values, error bars are SD,
*p<0.05 (n=9). Abbreviations: inner nuclear layer (INL); outer
nuclear layer ONL; and subretinal space (SRS).