Figure 1. Retinal flat mounts at P14 and
P18 in the ROP model and at P18 in RA samples. Representative
lectin-stained flat mounts from rat pups in the ROP model or RA
conditions. In the ROP model, avascular retina remains at P14 (A),
while
in
RA, intraretinal vascularization is complete at P14 (C).
In the ROP model, after seven cycles of oxygen fluctuations by P14,
pups are then moved into RA for 4 days. At P18, intravitreous
neovascularization occurs at the junction of vascularized and avascular
retina (B).