Table 3 of Tan, Mol Vis 2011; 17:1553-1558. Table 3 of Tan, Mol Vis 2011; 17:1553-1558.
Table 3. Frequencies of genotypes and alleles of EPHA2 polymorphisms in ARC patients and controls.
SNP |
Genotype allele |
ARC (%) (n=422) |
Controls (%) (n=317) |
χ2 |
p value |
pc value |
OR (95% CI) |
|---|---|---|---|---|---|---|---|
| rs3768293 | AA | 314 (74.41) | 210(66.25) | 5.845 | 0.016 | NS | 1.481 (1.076~2.039) |
| AC | 96 (22.75) | 99 (31.23) | 6.704 | 0.010 | NS | 0.648 (0.467~0.901) | |
| CC | 12 (2.84) | 8 (2.52) | 0.070 | 0.791 | NS | 1.130 (0.457~2.799) | |
| A | 724 (85.78) | 519 (81.86) | 4.162 | 0.041 | NS | 1.337 (1.011~1.768) | |
| C | 120 (14.22) | 115 (18.14) | 4.162 | 0.041 | NS | 0.748 (0.566~0.989) | |
| rs3754334 | CC | 301 (71.33) | 222 (70.03) | 0.147 | 0.702 | NS | 1.065 (0.773~1.466) |
| CT | 111 (26.30) | 84 (26.50) | 0.004 | 0.953 | NS | 0.990 (0.711~1.378) | |
| TT | 10 (2.37) | 11 (3.47) | 0.794 | 0.373 | NS | 0.675 (0.283~1.610) | |
| C | 713 (84.48) | 528 (83.28) | 0.386 | 0.534 | NS | 1.093 (0.826~1.445) | |
| T | 131 (15.52) | 106 (16.72) | 0.386 | 0.534 | NS | 0.915 (0.692~1.211) | |
| rs477558 | AA | 260 (61.61) | 161 (50.79) | 8.649 | 0.003 | 0.045 | 1.555 (1.158~2.089) |
| AG | 135 (31.99) | 136 (42.90) | 9.281 | 0.002 | 0.030 | 0.626 (0.463~0.847) | |
| GG | 27 (6.40) | 20 (6.31) | 0.002 | 0.961 | NS | 1.015 (0.558~1.845) | |
| A | 655 (77.61) | 458 (72.24) | 5.607 | 0.018 | NS | 1.332 (1.050~1.689) | |
| G | 189 (22.39) | 176 (27.76) | 5.607 | 0.018 | NS | 0.751 (0.592~0.952) | |
| rs707455 | TT | 218 (51.66) | 183 (57.73) | 2.687 | 0.101 | NS | 0.782 (0.583~1.049) |
| CT | 178 (42.18) | 122 (38.48) | 1.024 | 0.311 | NS | 1.166 (0.866~1.570) | |
| CC | 26 (6.16) | 12 (3.79) | 2.094 | 0.148 | NS | 1.669 (0.829~3.361) | |
| T | 614 (72.75) | 488 (76.97) | 3.404 | 0.065 | NS | 0.799 (0.629~1.014) | |
| C | 230 (27.25) | 146 (23.03) | 3.404 | 0.065 | NS | 1.252 (0.986~1.590) | |
| rs7548209 | GG | 302 (71.56) | 191 (60.25) | 10.430 | 0.001 | 0.015 | 1.660 (1.219~2.261) |
| CG | 110 (26.07) | 117 (36.91) | 9.999 | 0.002 | 0.030 | 0.603 (0.440~0.826) | |
| CC | 10 (2.37) | 9 (2.84) | 0.159 | 0.690 | NS | 0.831 (0.333~2.069) | |
| G | 714 (84.60) | 499 (78.71) | 8.537 | 0.003 | 0.015 | 1.486 (1.138~1.940) | |
| C | 130 (15.40) | 135 (21.29) | 8.537 | 0.003 | 0.015 | 0.673 (0.515~0.879) |