Figure 9. A schematic distribution showing
the eight disease-causing mutations in the Usher syndrome type IIA
(USH2A) isoform b protein domains identified in this study and in the
five disease-causing mutations (blue characters) from a previous study [
21]. Abbreviation:
Laminin G-like domain (Lam GL); Laminin N-terminal (Lam NT); Laminin
EGF-like domain (Lam EGF); Fibronectin type III (FN3); Laminin G
domains (Lam G); Transmembrane region (TM); and PDZ-binding motif (PBM).