Figure 1. The pedigrees of the four Chinese families with autosomal recessive retinitis pigmentosa (arRP) or Usher syndrome type II (USH2), and with mutations in the USH2A gene. Pedigree and haplotyping analyses of family one (FR1) showed segregation with six microsatellite markers on chromosome 1 listed in descending order from the centromeric end. Squares indicate males; circles indicate females; slashed symbols indicate deceased; solid symbols indicate affected; open symbols indicate unaffected; and arrow symbol indicates proband. The genotype of each evaluated individual is shown below the individual’s symbol and identification number. Abbreviations: Wild type (W); p.C934W (M1); p. W2744C (M2); p. R626X (M3); p. I2084fs (M4); p. W1263X (M5); p. D3165fs(M6); p.G2375fs (M7); p.Y4801X (M8).