Table 2 of Jia, Mol Vis 2011; 17:1493-1507.

Table 2. Relative expression (fold change of control) of Th17-associated and Treg-related factors at the mRNA level from the spleen during monophasic EAU with Lewis rats.

Genes
 con 7 d 14 d 21 d 28 d 35 d
Th17 related
IL-6 1.00 0.69 0.90 0.78 1.06 1.09
TGF-β 1.00 0.90 0.92 0.67 0.89 0.91
IL-23p19 1.00 0.97 1.11 0.90 1.27 1.24
IL-23 (−12) p40 1.00 0.60 0.76 0.85 0.75 0.86
IL-17 ND$ ND$ ND$ ND$ ND$ ND$
IL-17F ND$ ND$ ND$ ND$ ND$ ND$
IL-17R 1.00 1.24 0.97 0.90 0.82 1.10
CD4 1.00 0.88 0.99 0.87 1.01 0.91
MHC II 1.00 0.79 0.74 0.72 0.84 0.73
CD8 1.00 1.54 0.56 0.53 0.71 0.65
MHC I 1.00 0.91 0.81 0.84 0.99 0.91
RORγt 1.00 1.20 1.83 1.07 1.15 1.20
CCR6 1.00 0.63 0.71 0.68 0.85 0.80
Treg-related
Foxp3 1.00 0.90 0.82 0.70 0.87 0.82
CXCR5 1.00 1.04 0.99 0.90 0.94 1.17
CD25 1.00 0.95 0.97 0.80 0.89 0.81

Notes: con*, tissue counterparts were obtained from control Lewis rats, relative expression of the gene of interest was measured by the same method with the EAU rats and set as 1.00, respectively. ND$, the expression was too low to be detected. Genes showing at least a twofold change were recognized as being significantly altered.

Jia, Mol Vis 2011; 17:1493-1507. http://www.molvis.org/molvis/v17/a168

©2011 Molecular Vision http://www.molvis.org/molvis/

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