Figure 4. Effect of travoprost (0.004%, 30 μl) on IOP of conscious Tibetan monkeys. The drug was administered topically at 9 AM (Time 0) onto a randomly assigned eye of each animal, while the contralateral eye received vehicle as control. IOP was monitored at 3, 6, 24, and 48 h later. Error bars represent SEM (n=6). Top Panel: IOP values of both groups. ***p<0.001 between the two treatment groups by two-tailed paired Student's t-test. Bottom panel: % IOP change of the travoprost group relative to the vehicle control group.