Figure 2. Immunostaining for progenitor markers. In non-Sjögren syndrome, p63 (red) was expressed in 2–4 cells in each acinar unit (A) and all ductal basal cells (B; case 7). In Sjögren syndrome, p63 was weakly expressed with irregular pattern. (case 2; F, G). Nucleostemin was expressed with a similar pattern in non-Sjögren syndrome (case 7; C) and Sjögren syndrome (case 2; H). Nuclei were counterstained with DAPI (blue). ABCG2 (red) was expressed in intercellular junction and cytoplasm in acinar unit (F, I), and weaker in Sjögren syndrome. Nestin was expressed strongly in some location in Sjögren syndrome (E, J). Scale bars indicate 50 μm (A-C, E-H, J) and 20 μm (D, I), SS=Sjögren syndrome, non-SS=non Sjögren syndrome.