Figure 1. Pedigree drawings of families
PKRP161 and PKRP183 with haplotyes of five adjacent chromosomes 4p
microsatellite markers and variations identified in PDE6β. Single base
changes: c.1655G>A and c.1160C>T were identified in PKRP161 and
PKRP183, respectively and segregate with the disease phenotype in their
respective families. Squares: males; circles: females; filled symbols:
affected individuals; double lines between individuals: consanguineous
mating; and a diagonal line through a symbol: a deceased family member.
Alleles forming the risk haplotype are shaded black and alleles not
co-segregating with retinitis pigmentosa are shown in white.