Figure 4. Quantitative trait loci (QTL) Heat Map of the top 100 correlates of phosphatase tensin homolog (Pten). The numbers to the left denote the top 100 genes that correlate with Pten and the chromosomal location is noted at the bottom of the heat map ranging from chromosome 1 on the left to chromosome X on the right. The banding pattern is displayed in yellow, red, green, and blue, which denote the locations of the genomic loci that modulate all of the genes in the network. The green (low likelihood ratio statistic; LRS) to blue (high LRS) coloring represents transcripts whose expression is higher in the strains with a B haplotype (C57BL/6J) and the yellow (low LRS) to red (high LRS) coloring corresponds to the transcripts whose expression is higher in the strains with mutant D haplotype (DBA/2J). The red arrows indicate the most prominent bands with significant QTLs and portray the signature bands of the Pten network chromosomes 1, 2, 12, 15, 16, and 19.