Figure 4. Anti-integrin a2β1 and anti-integrin a1β1 affect on mechanical creep properties of collagen matrix. A: Typical extension-versus-time behavior of the samples was shown, respectively. A constantly applied load of 0.03 N for 600 s was subjected to each sample. B: Anti-integrin a2β1 and anti-integrin a1β1 acted on the final extension of the HSF-populated collagen gel. C: Anti-integrin a2β1 and anti-integrin a1β1 acted on creep extension of the HSF-populated collagen gel. D: Anti-integrin a2β1 and anti-integrin a1β1 acted on the creep rate of the HSF-populated collagen gel. Results were expressed as mean±SEM *p<0.01 versus CON;^#p<0.01 versus α2β1 (1 μg/ml) or α1β1 (1 μg/ml); †p<0.01 versus α1β1 (1 μg/ml) or α1β1 (4 μg/ml).