Table 1 of Law, Mol Vis 2011; 17:1231-1238.

Table 1. Clinical presentations of the two eyes of an individual with Axenfeld-Rieger syndrome.

Patient Year of Birth Sex Anterior segment phenotype of first eye Anterior segment phenotype of second eye Additional ocular findings Eye with Glaucoma Central corneal thickness (Right/Left eye) in micron Dental Abnormalities Umbilical Abnormalities
G.G. 1980 Male Axenfeld & Rieger anomalies Axenfeld & Rieger anomalies
Both eyes 560 / 545 Unknown Unknown
K.M. 1980 Male Rieger anomaly Rieger anomaly Optic nerve coloboma (right eye) Both eyes 616 / 616 Unknown Unknown
J.B.* 1990 Female Axenfeld anomaly Axenfeld anomaly Microcornea and scleral thinning (both eyes) None 576 / 606 Presence Presence
M.B.* 1960 Female Axenfeld & Rieger anomalies Axenfeld & Rieger anomalies Corneal scar and scleral thinning (left eye) Both eyes 571 / left corneal scar Presence Unknown
A.C. 1954 Male Axenfeld & Rieger anomalies Axenfeld & Rieger anomalies
Both eyes
Unknown Unknown
A.M. 2009 Female Rieger anomaly Rieger anomaly Cataract and corneal scar (both eyes) Both eyes
Unknown Absence
H.L. 1996 Male Axenfeld & Rieger anomalies Axenfeld & Rieger anomalies
Both eyes 626 / not measurable Presence Presence
M.A. 2003
 Female Axenfeld & Rieger anomalies Aniridia
Both eyes 664 / 683 Presence Presence

Signs of Axenfeld anomaly include: prominent schwalbe line, iris adhesion to cornea and trabecular meshwork. Signs of Rieger anomaly include: iris hypoplasia, correctopia or polycoria, ectropion uveae. *J.B. and M.B. had a mother-and-son relationship

Law, Mol Vis 2011; 17:1231-1238. http://www.molvis.org/molvis/v17/a138

©2011 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535