Table 5 of Paylakhi, Mol Vis 2011; 17:1209-1221.


Table 5. Functional annotations enriched for genes affected by PITX2 siRNAs*.

Category GO ID and Term Number of genes p value
GOTERM_CC_ALL GO:0016363~nuclear matrix 2 0.0013123
GOTERM_BP_ALL GO:0030098~lymphocyte differentiation 4 0.0013564
GOTERM_CC_ALL GO:0034399~nuclear periphery 2 0.001421
GOTERM_CC_ALL GO:0005789~endoplasmic reticulum membrane 3 0.0014526
KEGG_PATHWAY hsa04666:Fc gamma R-mediated phagocytosis 2 0.0020273
GOTERM_BP_ALL GO:0002520~immune system development 5 0.0026937
GOTERM_BP_ALL GO:0002521~leukocyte differentiation 4 0.0026975
GOTERM_MF_ALL GO:0019901~protein kinas binding 3 0.005062
GOTERM_MF_ALL GO:0030246~carbohydrate binding 4 0.0055687
GOTERM_MF_ALL GO:0019900~kinase binding 3 0.0071612
GOTERM_BP_ALL GO:0046649~lymphocyte activation 4 0.0086461
GOTERM_BP_ALL GO:0030097~hemopoiesis 4 0.0137107
GOTERM_BP_ALL GO:0006955~immune response 6 0.0145876
GOTERM_BP_ALL GO:0045321~leukocyte activation 4 0.0146618
GOTERM_CC_ALL GO:0042175~nuclear envelope-endoplasmic reticulum network 3 0.0158339
GOTERM_CC_ALL GO:0070160~occluding junction 2 0.0167652
GOTERM_CC_ALL GO:0005923~tight junction 2 0.0167652
GOTERM_BP_ALL GO:0048534~hemopoietic or lymphoid organ development 4 0.0177369
GOTERM_CC_ALL GO:0043232~intracellularnon-membrane-bounded organelle 10 0.0186364
GOTERM_CC_ALL GO:0043228~non-membrane-bounded organelle 10 0.0186364
GOTERM_CC_ALL GO:0009898~internal side of plasma membrane 3 0.0186943
GOTERM_CC_ALL GO:0044432~endoplasmic reticulum part 3 0.0215332
GOTERM_CC_ALL GO:0005783~endoplasmic reticulum 5 0.0216708
GOTERM_CC_ALL GO:0043296~apical junction complex 2 0.0220511
GOTERM_CC_ALL GO:0016327~apico lateral plasma membrane 2 0.0226397
GOTERM_BP_ALL GO:0001775~cell activation 4 0.0229807
GOTERM_CC_ALL GO:0005730~nucleolus 4 0.0253255
GOTERM_CC_ALL GO:0070013~intracellular organelle lumen 7 0.0281463
GOTERM_BP_ALL GO:0010557~positive regulation of macromolecule biosynthetic process 5 0.0492617