Figure 3. Effect of local HO-2 knockdown on the injury induced corneal neovascularization. A: Photographs showing neovascularization in control- and HO-2 shRNA-treated mice at days 4, and 7 after epithelial debridement. B: Neovascularization expressed as total length of penetrating vessels (***p<0.001 from control-shRNA-treated mice, n=10–21).