Table 2 of Kim, Mol Vis 2011; 17:1136-1143. Table 2 of Kim, Mol Vis 2011; 17:1136-1143.
Table 2. Association tests for three typed SNPs on 2p16.3.
| Group* | Genotype no. | Co-dominant model, p† | Dominant model | Statistical power‡ | |
|---|---|---|---|---|---|
| OR (95% CI)† | p† | ||||
| rs12994401 (C>T) | CC/CT/TT | ||||
| Controls (n=918) | 376/422/120 | – | 1 (reference) | – | – |
| Glaucoma (n=222) | 101/90/31 | 0.29 | 0.82 (0.61–1.10) | 0.18 | 100% |
| Open-angle | 81/76/29 | 0.37 | 0.89 (0.64–1.22) | 0.46 | 100% |
| High-tension | 76/70/27 | 0.36 | 0.87 (0.63–1.22) | 0.42 | 100% |
| Normal-tension | 5/6/2 | 0.97 | 1.10 (0.36–3.40) | 0.87 | – |
| Closed-angle | 20/14/2 | 0.13 | 0.51 (0.26–1.01) | 0.054 | – |
| rs1533428 (G>A) | GG/GA/AA | ||||
| Controls (n=923) | 355/443/125 | – | 1 (reference) | – | – |
| Glaucoma (n=222) | 96/102/24 | 0.37 | 0.82 (0.61–1.11) | 0.20 | 100% |
| Open-angle | 78/87/19 | 0.46 | 0.85 (0.62–1.18) | 0.33 | 100% |
| High-tension | 74/81/16 | 0.31 | 0.82 (0.59–1.15) | 0.25 | 100% |
| Normal-tension | 4/6/3 | 0.59 | 1.41 (0.43–4.63) | 0.58 | – |
| Closed-angle | 18/15/5 | 0.59 | 0.71 (0.36–1.37) | 0.30 | – |
| rs10202118 (T>C) | TT/TC/CC | ||||
| Controls (n=874) | 333/413/128 | – | 1 (reference) | – | – |
| Glaucoma (n=212) | 88/99/25 | 0.49 | 0.86 (0.63–1.18) | 0.35 | 86% |
| Open-angle | 71/85/20 | 0.58 | 0.90 (0.64–1.26) | 0.53 | 68% |
| High-tension | 68/79/17 | 0.39 | 0.86 (0.61–1.21) | 0.38 | 60% |
| Normal-tension | 3/6/3 | 0.50 | 1.84 (0.49–6.85) | 0.36 | – |
| Closed-angle | 17/14/5 | 0.66 | 0.73 (0.37–1.44) | 0.36 | – |