Table 2 of Sun, Mol Vis 2011; 17:997-1002.


Table 2. Apolipoprotein E (APOE) genotype and allele frequency distribution among study subjects.

    Cases with AMD
Genotype Controls Early AMD Exudative AMD
ε2ε2 0 (0) 2 (0.6%) 1 (0.7%)
ε2ε3 24 (11.9) 46 (12.7%) 20 (13.5%)
ε2ε4 3 (1.5%) 4 (1.1%) 4 (2.7%)
ε3ε3 146 (72.6%) 263 (72.5%) 104 (70.3%)
ε3ε4 24 (11.9%) 44 (12.1%) 19 (12.8%)
ε4ε4 4 (2.0%) 4 (1.1%) 0 (0)
Total 201 (100%) 363 (100%) 148 (100%)
P-value 0.885 0.416
H-W
χ2 6.265 1.846 2.994
p 0.099 0.605 0.393
Allele
ε2 27 (6.7%) 54 (7.4%) 26 (8.8%)
ε3 340 (84.6%) 616 (84.8%) 247 (83.4)
ε4 35 (8.7%) 56 (7.7%) 23 (7.8%)
Total 402 (100%) 726 (100%) 296 (100%)
p-value 0.776 0.558
Carrier
ε*2 24 (12.1%) 48 (13.4%) 21 (14.6%)
ε3ε3 146 (73.7%) 263 (73.3%) 104 (72.2%)
ε*4 28 (14.1%) 48 (13.4%) 19 (13.2%)
Total 198 (100%) 359 (100%) 144 (100%)
p-value 0.899 0.793