Figure 1. Representative anterior segment photographs from an AKC patient before and after treatment with tacrolimus ophthalmic solution. Anterior segment photograph (right) shows an extensive corneal damage visualized by the fluorescein staining. Note that the superficial punctate keratopathy is present in almost all the surface of the cornea and is associated to the increased papillary formation. The photographs on the left side represent the cornea and papillary formation from the same patient after 1 month of treatment with 0.1% tacrolimus ophthalmic solution. Note the improvement of the corneal damage as well as the decrease of papillary formation and conjunctival inflammatory status.