Table 3 of Gao, Mol Vis 2011; 17:903-919. Table 3 of Gao, Mol Vis 2011; 17:903-919.
Table 3. Significant mRNA level (fold) differences.
| Gene | Treated versus control | Treated or control versus normal | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lens wear | Recovery | Lens wear | Recovery | |||||||||||||
| 1 day | 4 days | 11 days | 1 day | 4 days | 1 day | 4 days | 11 days | 1 day | 4 days | |||||||
| Tvs24N | Cvs24N | Tvs24N | Cvs24N | Tvs38N | Cvs38N | Tvs38N | Cvs38N | Tvs38N | Cvs38N | 24N versus 38N | ||||||
| Signaling pathways | ||||||||||||||||
| TGFB1 | – | −1.4 | – | – | 1.2 | −1.3 | −1.4 | – | – | – | 1.5 | – | – | 1.4 | – | – |
| TGFB2 | – | −2.2 | – | −1.8 | 1.6 | −3.7 | −4.2 | – | – | – | – | – | – | 3.3 | 2.1 | −2.4 |
| TGFB3 | – | – | – | – | 1.8 | −2.1 | −2.6 | – | – | 2.1 | 2.1 | – | 1.6 | 2.5 | – | – |
| TGFBR1 | – | – | – | −1.9 | – | – | −2.0 | – | – | – | – | −1.8 | – | 2.0 | – | – |
| TGFBR2 | – | – | – | −1.6 | – | – | −1.5 | – | – | – | – | – | – | 1.5 | 1.5 | – |
| TGFBR3 | – | 1.7 | – | −3.1 | – | – | −3.3 | – | – | 2.0 | 2.1 | −2.9 | – | – | 2.1 | – |
| FGF2 | – | – | – | −1.6 | – | −1.8 | −2.1 | – | – | – | – | −1.8 | – | 1.6 | – | – |
| FGFR1 | – | – | – | – | – | −1.8 | −2.0 | – | – | – | – | – | – | 1.7 | – | – |
| APOE | – | – | – | – | – | – | – | – | – | – | – | – | – | −2.0 | −1.7 | – |
| APOA1 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Matricellular proteins | ||||||||||||||||
| THBS1 | – | −2.3 | – | – | – | −2.9 | −4.8 | −3.2 | – | – | 2.6 | – | – | 2.4 | – | – |
| THBS2 | – | – | – | – | 1.6 | – | −2.4 | – | – | – | – | −2.4 | – | 2.1 | – | – |
| TNC | – | −1.6 | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| SPARC | – | −1.4 | – | −1.7 | – | −2.3 | −3.1 | −1.7 | – | 1.8 | 2.3 | – | – | – | – | −1.6 |
| SPP1 | – | −1.4 | – | – | – | – | – | – | – | – | – | – | – | 1.6 | – | – |
| MPs/TIMPs | ||||||||||||||||
| MMP3 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 2.5 | – |
| MMP14 | – | 2.2 | – | – | – | – | – | 3.2 | – | −4.8 | −5.9 | −5.9 | −5.9 | – | – | – |
| ADAMTS1 | 2.8 | – | – | −4.0 | – | – | −4.2 | – | – | 2.0 | 2.7 | −6.3 | – | −1.6 | – | – |
| ADAMTS5 | – | −1.3 | – | −2.0 | – | −2.7 | −3.2 | – | – | – | – | −2.4 | – | 2.1 | 2.1 | −2.0 |
| TIMP3 | – | −2.8 | – | – | 2.0 | −2.7 | −3.0 | −2.7 | – | – | – | – | – | 2.6 | – | – |
| Cell adhesion/other | ||||||||||||||||
| SDC2 | – | – | – | – | – | – | −2.1 | – | – | – | – | – | – | 1.7 | – | – |
| SDC4 | – | – | – | −1.4 | – | – | – | – | – | – | – | – | – | – | – | – |
| VIM | – | – | – | – | – | – | – | – | – | – | – | – | – | −2.2 | −2.4 | – |
| COL6A1 | – | – | – | −1.8 | – | −2.2 | −3.4 | – | – | 1.6 | 1.8 | −2.0 | – | – | – | – |
| FN1 | – | – | – | – | – | −2.5 | −4.0 | – | – | 2.0 | 2.1 | – | – | 2.2 | – | −2.0 |
| PEDF | – | – | – | – | – | −1.9 | −2.5 | −1.7 | −1.4 | – | 1.7 | – | – | – | – | – |
| TGFBI | – | 1.9 | – | – | – | −1.7 | −2.1 | – | – | – | – | −3.1 | – | – | – | – |