Figure 4. Restriction fragment length
analysis of CRYGD exon 2. The mutation shows the gain of an
Alu1 site (AGkCT) that co-segregated with affected individuals
heterozygous for the C229A alteration (299,196, 69, and 35 bp), but not
with unaffected individuals (495, 69, and 35 bp). L=100bp DNA ladder,
U=undigested. Only one wild-type (III:3) is shown in the figure.