Figure 1. Cytokines and chemokines in tears of DED patients. Fourteen out of the 15 molecules analyzed were detected. EGF, Fractalkine/CX3CL1, IL-1Ra, IP-10/CXCL10, VEGF, and IL-8 were the more detected molecules in evaporative-type DED tear samples and were also the ones with the highest concentration. Data are presented on a logarithmic scale and bars represent values for OS and OD together. Percents of patients having detectable amounts are shown at the top of each bar. EGF, epidermal growth factor; IFN-γ, interferon gamma; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin; IL-1Ra, interleukin 1 receptor antagonist; TNFα, tumor necrosis factor alpha; IP-10, interferon inducible protein 10; VEGF, vascular endothelial growth factor.