Table 1 of
Mitra, Mol Vis 2010; 16:828-842. Table 1 of
Mitra, Mol Vis 2010; 16:828-842.
Table 1. Upregulated genes identified by microarray post EpCAM knock-down in Y79
| Gene classification/description | Gene symbol | Fold change | GenBank accession | Chromosome location |
|---|---|---|---|---|
| Cell cycle and cell differentiation | ||||
| Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, mRNA | LGALS3 | 1.036256 | [NM_002306] | 14q22.3 |
| Homo sapiens 5-hydroxytryptamine (serotonin) receptor 5A (HTR5A), mRNA | HTR5A | 1.283948 | [NM_024012] | 7q36.2 |
| Homo sapiens insulin (INS), mRNA | INS | 1.370663 | [NM_000207] | 11p15.5 |
| Homo sapiens tachykinin 3 (neuromedin K, neurokinin beta) (TAC3), transcript variant 1, mRNA | TAC3 | 1.281899 | [NM_001006667] | 12q13.3 |
| Homo sapiens activating transcription factor 3 (ATF3), transcript variant 2, mRNA | ATF3 | 2.262722 | [NM_004024] | 1q32.3 |
| Apoptosis | ||||
| Homo sapiens lactalbumin, alpha- (LALBA), mRNA | LALBA | 3.158096 | [NM_002289] | 12q13.2 |
| Homo sapiens retinoic acid receptor, gamma (RARG), transcript variant 1, mRNA | RARG | 1.541636 | [NM_000966] | 12q13.13 |
| Homo sapiens ataxin 3 (ATXN3), transcript variant 1, mRNA | ATXN3 | 2.464725 | [NM_004993] | 14q32.12 |
| Homo sapiens spectrin repeat containing, nuclear envelope 2 (SYNE2), transcript variant 2, mRNA | SYNE2 | 2.345608 | [NM_182910] | 14q23.2 |
| Homo sapiens mitogen-activated protein kinase 13 (MAPK13), mRNA | MAPK13 | 1.283948 | [NM_002754] | 6p21.31 |
| Homo sapiens tubulin, beta 2A (TUBB2A), mRNA | TUBB2A | 1.269632 | [NM_001069] | 6p25.2 |
| Homo sapiens plastin 3 (T isoform) (PLS3), mRNA | PLS3 | 1.596833 | [NM_005032] | Xq23 |
| Homo sapiens unc-13 homolog B (C. elegans) (UNC13B), mRNA | UNC13B | 1.084631 | [NM_006377] | 9p13.3 |
| Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 2 (BACH2), mRNA | BACH2 | 1.111043 | [NM_021813] | 6q15 |
| Homo sapiens activating transcription factor 3 (ATF3), transcript variant 2, mRNA | ATF3 | 2.262722 | [NM_004024] | 1q32.3 |
| Homo sapiens insulin-like growth factor binding protein 1 (IGFBP1), transcript variant 1, mRNA | IGFBP1 | 1.261051 | [NM_000596] | 7p13 |
| Homo sapiens protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform (PPP3R2), mRNA | PPP3R2 | 2.201001 | [NM_147180] | 9q31.1 |
| Homo sapiens androgen-induced 1 (AIG1), mRNA | AIG1 | 2.769478 | [NM_016108] | 6q24.2 |
| Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), mRNA | M6PR | 2.997706 | [NM_002355] | 12p13.31 |
| Homo sapiens hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (HADHA), nuclear gene encoding mitochondrial protein, mRNA | HADHA | 4.116386 | [NM_000182] | 2p23.3 |
| Homo sapiens transcription factor 25 (basic helix–loop–helix) | TCF25 | 2.112025 | [NM_014972] | 16q24.3 |
| Homo sapiens protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) (PRKRIR), mRNA | PRKRIR | 1.065873 | [NM_004705] | 8q21.12 |
| Homo sapiens cytochrome c, somatic (CYCS), nuclear gene encoding mitochondrial protein, mRNA | CYCS | 1.40148 | [NM_018947] | 7p15.2 |
| Homo sapiens damage-regulated autophagy modulator (DRAM), mRNA | DRAM | 4.908309 | [NM_018370] | 12q23.2 |
| Homo sapiens mRNA; cDNA DKFZp762K1914 (from clone DKFZp762K1914). | PNPT1 | 1.054391 | [CR749867] | 2p16.1 |
| Anti-Apoptosis | ||||
| Homo sapiens phosphodiesterase 3B, cGMP-inhibited (PDE3B), mRNA | PDE3B | 1.798894 | [NM_000922] | 11p15.2 |
| Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, mRNA | LGALS3 | 1.036256 | [NM_002306] | 14q22.3 |
| Homo sapiens adenosine A3 receptor (ADORA3), transcript variant 2, mRNA | ADORA3 | 1.177361 | [NM_000677] | 1p13.2 |
| Homo sapiens prostaglandin E receptor 4 (subtype EP4) (PTGER4), mRNA | PTGER4 | 1.424538 | [NM_000958] | 5p13.1 |
| Angiogenesis | ||||
| Homo sapiens fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) (FSCN1), mRNA | FSCN1 | 1.247566 | [NM_003088] | 7p22.1 |
| Anti-angiogenesis | ||||
| Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, mRNA | LGALS3 | 1.036256 | [NM_002306] | 14q22.3 |
| Homo sapiens vasohibin 1 (VASH1), mRNA | VASH1 | 1.085812 | [NM_014909] | 14q24.3 |
| Proliferation | ||||
| Homo sapiens jumonji domain containing 2C (JMJD2C), mRNA [NM_015061] | JMJD2C | 1.889542 | [NM_015061] | 9p24.1 |
| Homo sapiens adenosine A3 receptor (ADORA3), transcript variant 2, mRNA | ADORA3 | 1.177361 | [NM_000677] | 1p13.2 |
| Homo sapiens tachykinin 3 (neuromedin K, neurokinin beta) (TAC3), transcript variant 1, mRNA | TAC3 | 1.281899 | [NM_013251] | 12q13.3 |
| Anti-proliferation | ||||
| Homo sapiens spectrin repeat containing, nuclear envelope 2 (SYNE2), transcript variant 2, mRNA | SYNE2 | 2.345608 | [NM_182910] | 14q23.2 |
| Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, mRNA | LGALS3 | 1.036256 | [NM_002306] | 14q22.3 |
| Homo sapiens BTB and CNC homology 1, basic leucine zipper transcription factor 2 (BACH2), mRNA | BACH2 | 1.111043 | [NM_021813] | 6q15 |
| Homo sapiens tripartite motif-containing 8 (TRIM8), mRNA | TRIM8 | 3.145901 | [NM_030912] | 10q24.32 |
| Homo sapiens Rac GTPase activating protein 1 (RACGAP1), mRNA | RACGAP1 | 1.167279 | [NM_013277] | 12q13.13 |
| Homo sapiens cDNA FLJ41884 fis, clone OCBBF2023162. | MEG3 | 1.066443 | [AK123878] | 14q32.2 |
| Tumor suppressor | ||||
| Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 6, mRNA | TPM1 | 1.539701 | [NM_001018008] | 15q22.2 |