Figure 4. Suppression of laser photocoagulation-induced choroidal neovascularization by thioredoxin-vasostatin 48 eyedrops. A: Representative choroidal neovascularization (CNV) lesion in the eyes of rats treated with topical thioredoxin eyedrops (left) or topical thioredoxin-vasostatin 48 eyedrops (right) as identified by fluorescent angiography (FA) on day 21. B: The areas of CNV lesions were determined by FA examination on days 21, 28, 35, and 42 after laser photocoagulation. Data are summarized as mean + SEM (n=8). Double asterisk (**) represents p<0.01).