Figure 2. Effect of thioredoxin-vasostatin 48 on the vessel networks in rat aorta rings. A: The profile of micro-vessel outgrowth in rat aorta arteries treated with thioredoxin (TRX), TRX-fused vasostatin 48 (TRX-VS48), and control. After 5 days, the greatest distance from the aortic ring body to the end of the vascular sprouts was measured in three different rings per group. Magnification is 20×. B: Vessel sprouting was significantly attenuated by TRX-VS48. Data represents the mean±SD of quadruplicate experiments *(p<0.01).